Melanotan-1 10mg
$28.00
Melanotan 1 is an experimental peptide that mimics a natural hormone in your body to increase melanin production, which darkens the skin. It was developed mainly to help people with rare skin disorders who are extremely sensitive to sunlight. Unlike Melanotan 2, it generally has fewer side effects and doesn’t usually affect sexual function. While it’s approved in some places as a prescription implant for specific medical conditions, it’s not approved for cosmetic tanning in most countries.
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Melanotan 1
- Form: Lyophilized powder
- Purity: >99%
Overview
Melanotan 1 is a synthetic peptide analog of alpha-melanocyte–stimulating hormone (α-MSH). It is composed of 13 amino acids, the same as α-MSH, but differs by two substitutions: methionine and L-phenylalanine at the fourth and seventh positions are replaced with norleucine and D-phenylalanine. These modifications are thought to increase receptor affinity and extend half-life. Melanotan 1 has been studied for its potential to stimulate melanocortin receptors (MCRs) and promote eumelanin production, contributing to photoprotection and pigmentation.
Research Background
Eumelanin is a pigment that may protect skin and tissues from UV-induced damage. Research suggests Melanotan 1 mimics the natural activity of α-MSH but with greater stability and stronger binding to melanocortin 1 receptors (MC1R). This may enhance melanin production and lead to increased pigmentation even in the absence of sunlight exposure.
Mechanism of Interest
- MC1R activation: Melanotan 1 is thought to preferentially bind to melanocortin 1 receptors, promoting melanin synthesis.
- cAMP signaling: Activation of MC1R may trigger cAMP production, which stimulates microphthalmia transcription factor (MITF) expression and the enzymes necessary for eumelanin synthesis.
- Photoprotection: Increased eumelanin production may protect tissues from UV damage and oxidative stress.
Molecular Information
- Molecular Formula: C78H111N21O19
- Molecular Weight: 1646.87 g/mol
- Other Names: MT1, Afamelanotide
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Melanotan-1 10mg