Pinealon 20mg

Pinealon 20mg

• Form: Lyophilized powder
• Purity: >99%

Overview

Pinealon is a short synthetic tripeptide composed of Glu–Asp–Arg, also known as the EDR peptide. It has been studied for its potential to impact the central nervous system, including possible neuroprotective, antioxidant, and anti-apoptotic effects. Research suggests Pinealon may penetrate the blood–brain barrier and interact with DNA molecules, raising interest in its potential role in brain health and cellular protection.

Research Background

Pinealon is derived from Cortexin, a low–molecular weight polypeptide studied for its ability to cross the blood–brain barrier and stimulate neurotransmitter activity. Experimental findings indicate Pinealon may influence neuronal survival, oxidative stress response, and cell cycle modulation. Its biological activity appears to be concentration-dependent: at lower levels it may act primarily as an antioxidant, while at higher levels it may interact with DNA and influence gene regulation.

Mechanism of Interest

• MAPK/ERK signaling: Suggested to modulate pathways linked to neuron plasticity, metabolic stress, and apoptosis.
• Oxidative stress reduction: May decrease the synthesis of reactive oxygen species (ROS), potentially lowering stress-induced cell damage.
• Cell cycle modulation: Higher concentrations may influence genomic interactions and alter cell cycle progression.
• Neuroprotection: Studied for protective effects on neurons and other cell types against oxidative stress.

Molecular Information

• Molecular Formula: C15H26N6O8
• Molecular Weight: 418.4 g/mol
• Other Names: EDR, Glu–Asp–Arg